NS 13001
Catalogue number:
CAY37317-25 mg
Supplier:
Size:
25 mg
Product is available in:
£984.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1063331-94-1
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
353.8
Alternative Names:
n-(4-chlorophenyl)-2-(3,5-dimethyl-1h-pyrazol-1-yl)-9-methyl-9h-purin-6-amine
- Data sheet: View or download
- MSDS: View or download
Product Description:
A positive allosteric modulator of KCa2.2/SK2 and KCa2.3/SK3; increases calcium-induced currents in an inside-out patch clamp assay using HEK293 cells expressing human KCa2.2/SK2 or KCa2.3/SK3 (EC50s = 1.8 and 0.14 µM, respectively); improves sensorimotor deficits in the beam walk test and increases the latency to fall in the rotarod test in a SCA2-58Q transgenic mouse model of neuromuscular degeneration at 30 mg/kg per day, p.o.
Storage Temperature:
-20°C