10074-A4
Catalogue number:
CAY37486-5 mg
Supplier:
Size:
5 mg
Product is available in:
£210.00
Estimated delivery Fri 9 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
312631-87-1
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
409.3
Alternative Names:
3-[3-(3,6-dichloro-9h-carbazol-9-yl)-2-hydroxypropyl]-2,4-thiazolidinedione
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of the protein-protein interaction between c-Myc and Max; inhibits c-Myc and Max heterodimerization at 5 µM and the proliferation of Rat1 and TGR-1 rat fibroblasts but not TGR-1 Myc knockout fibroblasts at 32 µM; reduces the expression of the gene encoding ODC and induces cell cycle arrest at the G0/G1 phase in Myc-overexpressing Rat1 cells at 32 µM; preincubation of 10074-A4 at 32 µM with Myc-overexpressing Rat1 cells in vitro reduces tumor growth of the same cells in a mouse xenograft model.
Storage Temperature:
-20°C