£432.00
Estimated delivery Fri 9 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1392816-46-4
Purity:
≥95%
Formulation:
A solid
Molecular Weight:
400.5
Alternative Names:
2-[[1-(2-phenylethenyl)-4-[(2-phenylethyl)amino]-1h-pyrazolo[3,4-d]pyrimidin-6-yl]amino]-ethanol
- Data sheet: View or download
- MSDS: View or download
Product Description:
An SGK1 inhibitor (IC50 = 600 nM); selective for SGK1 over c-Src and Abl kinases at 12.5 µM; is cytotoxic to MCF-7, A172, and RKO cell lines at 12.5 µM; reduces tumor volume, tumor weight, and SGK1 protein levels in a PDX mouse model of ovarian cancer at 9.3 mg/kg in combination with paclitaxel; active against S. aureus and E. coli at 100 µg/ml
Storage Temperature:
-20°C