ICEC0942 (hydrochloride)
Catalogue number:
CAY30997-1 mg
Supplier:
Size:
1 mg
Product is available in:
£108.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1805789-54-1
Purity:
≥95%
Formulation:
A solid
Molecular Weight:
431
Alternative Names:
(3r,4r)-4-[[[3-(1-methylethyl)-7-[(phenylmethyl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]-3-piperidinol, monohydrochloride
- Data sheet: View or download
- MSDS: View or download
Product Description:
A Cdk7 inhibitor (IC50 = 0.04 µM); selective for Cdk7 over Cdk1, -2, -4, -5, -6, and -9 (IC50s = 1.8, 0.62, 49, 9.4, 34, and 1.2 µM, respectively); induces cell cycle arrest at the G2/M phase and apoptosis in HCT116 cells; reduces tumor growth in MCF-7 and HCT116 mouse xenograft models at 100 mg/kg
Storage Temperature:
-20°C