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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1334719-95-7
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
557
Alternative Names:
6-chloro-2-ethyl-n-[[4-[4-[4-(trifluoromethoxy)phenyl]-1-piperidinyl]phenyl]methyl]-imidazo[1,2-a]pyridine-3-carboxamide, telacebec
- Data sheet: View or download
- MSDS: View or download
Product Description:
An imidazopyridine amide antibiotic; active against M. tuberculosis and M. ulcerans (MIC50s = 2.7 and 0.86 nM, respectively); binds to the oxidation site on mitochondrial complex III and disrupts ATP synthesis in M. tuberculosis (IC50 = 1.1 nM); reduces bacterial load, as well as the number of lung CFUs and granulomatous foci in a mouse model of M. tuberculosis infection at 10 mg/kg for three days
Storage Temperature:
-20°C