£625.00
Estimated delivery Tue 16 Jul
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2226664-93-1
Purity:
≥95%
Formulation:
A solid
Molecular Weight:
360.2
Alternative Names:
5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2h-indol-2-ylidene]-1,3-dihydro-2h-indol-2-one
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of the CF5-Dvl protein-protein interaction (IC50 = 19 nM); an inhibitor of GSK3β (IC50 = 10 nM); increases expression of the mRNA encoding WISP-1 and Axin2, markers of Wnt pathway activation, in ATDC-5 chondrogenic cells at 100 nM; increases nuclear and cytosolic levels of β-catenin in ATDC-5 cells at 100 nM; increases bone plate growth and tibia length in adolescent mice at 0.1 mg/kg per day
Storage Temperature:
-20°C