LDE225 (phosphate)
Catalogue number:
CAY16263-10 mg
Supplier:
Size:
10 mg
Product is available in:
£258.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1218778-77-8
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
681.5
Alternative Names:
rel-n-[6-[(2r,6s)-2,6-dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide, diphosphate, erismodegib, nvp-lde225, sonidegib
- Data sheet: View or download
- MSDS: View or download
Product Description:
A Smo antagonist (IC50s = 1.3 and 2.5 nM for mouse and human Smo, respectively); inhibits Gli1 mRNA expression and prevents tumor growth in an orthotopic Ptch+/- p53-/- medulloblastoma mouse allograft model at 20 mg/kg per day
Storage Temperature:
-20°C
