PF-299804
Catalogue number:
CAY9001879-5 mg
Supplier:
Size:
5 mg
Product is available in:
£251.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1110813-31-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
469.9
Alternative Names:
n-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-(2e)-butenamide, dacomitinib, pf-299
- Data sheet: View or download
- MSDS: View or download
Product Description:
An irreversible pan-ErbB receptor tyrosine kinase inhibitor (IC50s = 6, 45.7, and 73.7 nM for ErbB1, ErbB2, and ErbB4, respectively); demonstrates antitumor activity in various tumor xenograft models expressing either wild-type ErbB or mutant ErbB family members that show resistance to first generation ErbB kinase inhibitors
Storage Temperature:
-20°C