GNF-5837
Catalogue number:
CAY14883-1 mg
Supplier:
Size:
1 mg
Product is available in:
£74.00
Estimated delivery Wed 7 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1033769-28-6
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
535.5
Alternative Names:
n-[3-[[2,3-dihydro-2-oxo-3-(1h-pyrrol-2-ylmethylene)-1h-indol-6-yl]amino]-4-methylphenyl]-n'-[2-fluoro-5-(trifluoromethyl)phenyl]-urea
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent, bioavailable pan-Trk inhibitor that blocks the proliferation of cells expressing TEL-TrkA, TEL-TrkB, and TEL-TrkC (IC50s = 7, 9, and 11 nM, respectively); inhibits the growth of Ba/F3 and RIE cells expressing both TrkA and NGF with IC50 values of 42 and 17 nM, respectively
Storage Temperature:
-20°C