JW 74
Catalogue number:
CAY19124-10 mg
Supplier:
Size:
10 mg
Product is available in:
£220.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
863405-60-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
456.5
Alternative Names:
4-[4-(4-methoxyphenyl)-5-[[[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]thio]-4h-1,2,4-triazol-3-yl]-pyridine
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of the catalytic PARP domain of TNKS1/2 that blocks canonical Wnt signaling with an IC50 value of 790 nM; decreases β-catenin levels in colorectal cancer (CRC) cells, leading to down-regulation of Wnt target genes; inhibits the growth of CRC xenograft tumors in mice
Storage Temperature:
-20°C
