Tonabersat
Catalogue number:
CAY19796-1 mg
Supplier:
Size:
1 mg
Product is available in:
£48.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
175013-84-0
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
391.8
Alternative Names:
n-[(3s,4s)-6-acetyl-3,4-dihydro-3-hydroxy-2,2-dimethyl-2h-1-benzopyran-4-yl]-3-chloro-4-fluoro-benzamide, sb-220453
- Data sheet: View or download
- MSDS: View or download
Product Description:
An anti-migraine agent; binds to connexin43 hemichannels and inhibits ATP release in vitro during injury and reperfusion in a dose-dependent manner; blocks trigeminal ganglion neuronal-satellite glial cell signaling and cortical spreading depression; in vivo (10 mg/kg) increases the seizure threshold in MEST mice and rats (143 and 1192%, respectively); blocks neurogenic plasma extravasation in a rat trigeminal nerve migraine model
Storage Temperature:
-20°C
