Napabucasin
Catalogue number:
CAY22255-50 mg
Supplier:
Size:
50 mg
Product is available in:
£651.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
83280-65-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
240.2
Alternative Names:
2-acetyl-naphtho[2,3-b]furan-4,9-dione, bbi 608
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of cancer cell stemness; reduces growth in a panel of cancer cells enriched for high stemness (IC50s = 0.291-1.249 µM); decreases protein and gene expression of various self-renewal and pro-survival markers in FaDu HNSCC cells; inhibits tumor growth in a PaCa-2 mouse xenograft model and prevents tumor regrowth after cessation of treatment (20 mg/kg per day); blocks formation of spleen and liver metastases in an HT29 ISMS model; reduces tumor volume in PC3 and 22RV1 prostate cancer mouse xenograft models (40 mg/kg)
Storage Temperature:
-20°C
