SAR7334 (hydrochloride)
Catalogue number:
CAY28292-1 mg
Supplier:
Size:
1 mg
Product is available in:
£89.00
Estimated delivery Fri 9 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1333207-63-8
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
440.8
Alternative Names:
4-[[(1r,2r)-2-[(3r)-3-amino-1-piperidinyl]-2,3-dihydro-1h-inden-1-yl]oxy]-3-chloro-benzonitrile, dihydrochloride
- Data sheet: View or download
- MSDS: View or download
Product Description:
A TRPC6 channel blocker (IC50 = 7.9 nM); selective for TRPC6 over TRPC4 and TRPC5 (IC50s = 282 and 226 nM, respectively); blocks TRPC6-dependent hypoxia-induced vasoconstriction in isolated perfused and ventilated mouse lung from 0.2-1 µM; inhibits oxidative stress-induced apoptosis and increases autophagic flux in primary mouse renal proximal tubule cells
Storage Temperature:
-20°C
