This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1797432-62-2
Purity:
98.87
Molecular Formula:
C21H19FN8O2
Molecular Weight:
434.43
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Tyk2-IN-5 (compound 6) is a potent, selective and orally active tyrosine kinase 2 (Tyk2) inhibitor that acts on the JH2 structural domain. Tyk2-IN-5 shows a Ki value of 0.086 nM for Tyk2 JH2 and an IC50 value of 25 nM for IFNα. Tyk2-IN-5 efficiently inhibits the production of IFNγ in a pharmacodynamic rat model and is fully efficacious in a rat model of arthritis[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)
