AZD 3229
Catalogue number:
CAY27908-5 mg
Supplier:
Size:
5 mg
Product is available in:
£371.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2248003-60-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
479.5
Alternative Names:
n-[4-[[5-fluoro-7-(2-methoxyethoxy)-4-quinazolinyl]amino]phenyl]-4-(1-methylethyl)-1h-1,2,3-triazole-1-acetamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of c-Kit-driven cell proliferation; selectively inhibits growth of c-Kit mutant (GI50s = 1-971 nM) and PDGFR mutant (GI50s = 1-22 nM) Ba/F3 cell lines over Ba/F3 cell lines expressing Tel-KDR/VEGFR2 (GI50 = 1,378 nM); induces tumor regression in a Ba/F3 mouse xenograft model at 20 mg/kg per day; induces tumor regression in a mouse allograft model using Ba/F3 cells expressing KIT-exon 11 del/V654A at 20 mg/kg twice per day
Storage Temperature:
-20°C
