LY3214996
Catalogue number:
CAY27936-1 mg
Supplier:
Size:
1 mg
Product is available in:
£74.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1951483-29-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
453.6
Alternative Names:
5,6-dihydro-6,6-dimethyl-2-[2-[(1-methyl-1h-pyrazol-5-yl)amino]-4-pyrimidinyl]-5-[2-(4-morpholinyl)ethyl]-4h-thieno[2,3-c]pyrrol-4-one
- Data sheet: View or download
- MSDS: View or download
Product Description:
An ERK1/2 inhibitor (IC50 = 5 nM for both); inhibits cell proliferation of tumor cells in vitro, including those expressing B-RAF, N-Ras, or K-Ras mutations in vitro; inhibits tumor growth in B-RAF or N-Ras mutant melanoma, B-RAF or K-Ras mutant colorectal, lung, and pancreatic cancer mouse xenograft models, as well as PDX mouse models
Storage Temperature:
-20°C