£238.00
Estimated delivery Fri 2 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
216167-82-7
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
616.9
Alternative Names:
butanedioic acid, 1-[4-[[1-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenyl] ester, agi-1067, probucol monosuccinate
- Data sheet: View or download
- MSDS: View or download
Product Description:
A probucol derivative with diverse biological activities; inhibits hydrogen peroxide-induced oxidation of the redox-sensitive dye H2DCF in HPAECs and U937 cells at 5 and 10 µM; reduces LPS-induced production of IL-6, IL-1β, and TNF-α in PBMCs from 0.3-10 µM; lowers plasma LDL levels and increases HDL levels in hypercholesterolemic cynomolgus monkeys at 50 and 100 mg/kg; inhibits the formation of aortic atherosclerotic plaques in ApoE-/- or Ldlr-/- mice
Storage Temperature:
-20°C